1637329-79-3

1637329-79-3 structure
1637329-79-3 structure
  • Name: Propargyl-PEG2-urea-C3-triethoxysilane
  • Chemical Name: Propargyl-PEG2-urea-C3-triethoxysilane
  • CAS Number: 1637329-79-3
  • Molecular Formula: C17H34N2O6Si
  • Molecular Weight: 390.55
  • Catalog: Signaling Pathways PROTAC PROTAC Linker
  • Create Date: 2021-09-12 09:14:30
  • Modify Date: 2024-01-10 13:34:11
  • Propargyl-PEG2-urea-C3-triethoxysilane is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name Propargyl-PEG2-urea-C3-triethoxysilane
Description Propargyl-PEG2-urea-C3-triethoxysilane is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Molecular Formula C17H34N2O6Si
Molecular Weight 390.55