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1442466-57-0

1442466-57-0 structure
1442466-57-0 structure
  • Name: t-Butyl acetate-PEG3-CH2COOH
  • Chemical Name: t-Butyl acetate-PEG3-CH2COOH
  • CAS Number: 1442466-57-0
  • Molecular Formula: C14H26O8
  • Molecular Weight: 322.35
  • Catalog: Signaling Pathways PROTAC PROTAC Linker
  • Create Date: 2021-09-10 21:59:27
  • Modify Date: 2024-01-12 17:15:56
  • t-Butyl acetate-PEG3-CH2COOH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name t-Butyl acetate-PEG3-CH2COOH
Description t-Butyl acetate-PEG3-CH2COOH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Molecular Formula C14H26O8
Molecular Weight 322.35