2412056-48-3

2412056-48-3 structure

Name: Thalidomide-NH-PEG4-COOH
Chemical Name: Thalidomide-NH-PEG4-COOH
CAS Number: 2412056-48-3
Molecular Formula: C₂₄H₃₁N₃O₁₀
Molecular Weight: 521.52
Catalog: Signaling Pathways PROTAC E3 Ligase Ligand-Linker Conjugate
Create Date: 2021-09-11 17:10:35
Modify Date: 2024-01-16 11:38:59
Thalidomide-NH-PEG4-COOH is an E3 ligase ligand-linker conjugate which can be used for synthesizing dCBP-1 (HY-134582). dCBP-1 is a potent and selective heterobifunctional degrader of p300/CBP[1].

Name	Thalidomide-NH-PEG4-COOH

Description	Thalidomide-NH-PEG4-COOH is an E3 ligase ligand-linker conjugate which can be used for synthesizing dCBP-1 (HY-134582). dCBP-1 is a potent and selective heterobifunctional degrader of p300/CBP[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> E3 Ligase Ligand-Linker Conjugate
Target	Cereblon
In Vitro	Thalidomide-NH-PEG4-COOH (S13) is the E3 ligase ligand-linker conjugate of dCBP-1 (HY-134582)[1].
References	[1]. Raghu Vannam, et al. Targeted degradation of the enhancer lysine acetyltransferases CBP and p300. Cell Chem Biol. 2020 Dec 31;S2451-9456(20)30513-4.