2368978-96-3

2368978-96-3 structure
2368978-96-3 structure
  • Name: Trx-red
  • Chemical Name: Trx-red
  • CAS Number: 2368978-96-3
  • Molecular Formula: C29H32ClN3O12S2
  • Molecular Weight: 714.16
  • Catalog: Research Areas Others
  • Create Date: 2021-09-11 19:31:35
  • Modify Date: 2025-08-26 11:19:59
  • Trx-red (NBL-SS perchlorate) is a red-emitting fluorescent probe derivatized from the nile blue fluorophore. Trx-red is used for selectively imaging thioredoxin (Trx) in live cells and in vivo (λex=615 nm, λem=661 nm)[1].

Name Trx-red
Description Trx-red (NBL-SS perchlorate) is a red-emitting fluorescent probe derivatized from the nile blue fluorophore. Trx-red is used for selectively imaging thioredoxin (Trx) in live cells and in vivo (λex=615 nm, λem=661 nm)[1].
Related Catalog
In Vitro Trx-red (NBL-SS) displayed multiple favorable properties, such as red emission, fast response, and high fluorescence signal. Thioredoxin (Trx) is a ubiquitous redox-regulating protein essentially involved in cell growth, differentiation, and death[1]. When HeLa cells are incubated with Trx-red (NBL-SS; 5 μM; 0-30 min), a clear time-dependent increase of the fluorescence is observed[1].
In Vivo Trx-red (NBL-SS; 10 μM; 30 min) is also suitable to image thioredoxin in 6 day-old zebrafish larvae[1].
References

[1]. Huiyi Jia, et al. Fluorophore-Dependent Cleavage of Disulfide Bond Leading to a Highly Selective Fluorescent Probe of Thioredoxin. Anal Chem. 2019 Jul 2;91(13):8524-8531.

Molecular Formula C29H32ClN3O12S2
Molecular Weight 714.16
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