1171341-19-7

1171341-19-7 structure

Name: VA-K-14 hydrochloride
Chemical Name: N-Methyl-4-(2-phenyl-1H-indol-3-yl)-1,3-thiazol-2-amine
CAS Number: 1171341-19-7
Molecular Formula: C₁₈H₁₆ClN₃S
Molecular Weight: 305.397
Catalog: Signaling Pathways GPCR/G Protein TSH Receptor
Create Date: 2021-09-13 10:54:32
Modify Date: 2024-01-09 20:02:20
VA-K-14 hydrochloride is a specific thyroid-stimulating hormone receptor (TSHR) antagonist (IC50= 12.3 μM)[1].

Name	N-Methyl-4-(2-phenyl-1H-indol-3-yl)-1,3-thiazol-2-amine
Synonyms	MFCD10180795 2-Thiazolamine, N-methyl-4-(2-phenyl-1H-indol-3-yl)- N-Methyl-4-(2-phenyl-1H-indol-3-yl)-1,3-thiazol-2-amine

Description	VA-K-14 hydrochloride is a specific thyroid-stimulating hormone receptor (TSHR) antagonist (IC50= 12.3 μM)[1].
Related Catalog	Research Areas >> Endocrinology Signaling Pathways >> GPCR/G Protein >> TSH Receptor
References	[1]. Latif R, et al. TSH Receptor Signaling Abrogation by a Novel Small Molecule. Front Endocrinol (Lausanne). 2016;7:130. Published 2016 Sep 27.