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381186-64-7

381186-64-7 structure
381186-64-7 structure
  • Name: RBC6
  • Chemical Name: 6-Amino-4-(3,5-dichloro-2-hydroxyphenyl)-3-propyl-2,4-dihydropyrano[2,3-c]pyrazole-5-carbonitrile
  • CAS Number: 381186-64-7
  • Molecular Formula: C16H14Cl2N4O2
  • Molecular Weight: 365.214
  • Catalog: Research Areas Cancer
  • Create Date: 2021-10-31 15:35:28
  • Modify Date: 2025-08-25 11:32:33
  • RBC6 is an inhibitor of GTPases RalA. RBC6 inhibits binding of Ral to its effector RALBP1. RBC6 also inhibits Ral-mediated cell spreading of murine embryonic fibroblasts, as well as anchorage-independent growth of human cancer celllines[1].

Name 6-Amino-4-(3,5-dichloro-2-hydroxyphenyl)-3-propyl-2,4-dihydropyrano[2,3-c]pyrazole-5-carbonitrile
Synonyms 6-Amino-4-(3,5-dichloro-2-hydroxyphenyl)-3-propyl-2,4-dihydropyrano[2,3-c]pyrazole-5-carbonitrile
Pyrano[2,3-c]pyrazole-5-carbonitrile, 6-amino-4-(3,5-dichloro-2-hydroxyphenyl)-2,4-dihydro-3-propyl-
Description RBC6 is an inhibitor of GTPases RalA. RBC6 inhibits binding of Ral to its effector RALBP1. RBC6 also inhibits Ral-mediated cell spreading of murine embryonic fibroblasts, as well as anchorage-independent growth of human cancer celllines[1].
Related Catalog
References

[1]. Yan C, et al. Discovery and characterization of small molecules that target the GTPase Ral. Nature. 2014 Nov 20;515(7527):443-7.  

Density 1.6±0.1 g/cm3
Boiling Point 544.8±50.0 °C at 760 mmHg
Molecular Formula C16H14Cl2N4O2
Molecular Weight 365.214
Flash Point 283.3±30.1 °C
Exact Mass 364.049377
LogP 3.75
Vapour Pressure 0.0±1.5 mmHg at 25°C
Index of Refraction 1.691
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