1375637-35-6

1375637-35-6 structure

Name: LY2880070
Chemical Name: (R)-N-(3-(2-methoxy-6-methylpyridin-3-yl)-1H-pyrazol-5-yl)-6-(piperidin-3-yloxy)pyrazin-2-amine
CAS Number: 1375637-35-6
Molecular Formula: C₁₉H₂₃N₇O₂
Molecular Weight: 381.43
Catalog: Signaling Pathways Cell Cycle/DNA Damage Checkpoint Kinase (Chk)
Create Date: 2021-09-11 18:36:44
Modify Date: 2025-08-26 16:43:08
LY2880070 is an orally active CHK1 inhibitor. LY2880070 can be used as an anticancer agent for combination with DNA damaging agents[1].

Name	(R)-N-(3-(2-methoxy-6-methylpyridin-3-yl)-1H-pyrazol-5-yl)-6-(piperidin-3-yloxy)pyrazin-2-amine

Description	LY2880070 is an orally active CHK1 inhibitor. LY2880070 can be used as an anticancer agent for combination with DNA damaging agents[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Cell Cycle/DNA Damage >> Checkpoint Kinase (Chk)
Target	1375637-35-6
References	[1]. Quincy S, et al. A phase Ib study of oral Chk1 inhibitor LY2880070 in combination with gemcitabine in patients with advanced or metastatic cancer. Journal of Clinical Oncology 2020 38:15_suppl, 3581.

Molecular Formula	C₁₉H₂₃N₇O₂
Molecular Weight	381.43