1263629-39-5

1263629-39-5 structure

Name: 1-[(2-chloro-5-thiazolyl)methyl]-3-(3,5-dichlorophenyl)-2-hydroxy-9-methyl-4-oxo-4H-pyrido[1,2-a]pyrimidinium inner salt
Chemical Name: dicloromezotiaz
CAS Number: 1263629-39-5
Molecular Formula: C₁₉H₁₂Cl₃N₃O₂S
Molecular Weight: 452.741
Catalog: Signaling Pathways Membrane Transporter/Ion Channel nAChR
Create Date: 2021-09-12 14:03:19
Modify Date: 2024-01-09 11:41:47
Dicloromezotiaz is a potent insecticide acting on nicotinic acetylcholine receptors (nAChRs). Dicloromezotiaz can be used to control a broad range of lepidoptera[1].

Name	dicloromezotiaz
Synonyms	1-[(2-Chloro-1,3-thiazol-5-yl)methyl]-3-(3,5-dichlorophenyl)-9-methyl-2,4-dioxo-3,4-dihydro-2H-pyrido[1,2-a]pyrimidin-1-ium-3-ide 1-[(2-Chloro-5-thiazolyl)methyl]-3-(3,5-dichlorophenyl)-9-methyl-2,4-dioxo-2H-pyrido[1,2-a]pyrimidinium inner salt dicloromezotiaz T66 ANV DVNJ CR CG DG& G1 E1- DT5N CSJ BG &&anhydro 2H-Pyrido[1,2-a]pyrimidinium, 1-[(2-chloro-5-thiazolyl)methyl]-3-(3,5-dichlorophenyl)-3,4-dihydro-9-methyl-2,4-dioxo-, inner salt 1-(2-Chlorothiazol-5-ylmethyl)-3-(3,5-dichlorophenyl)-3,4-dihydro-9-methyl-2,4-dioxo-2H-pyrido[1,2-a]pyrimidin-1-ium-3-ide

Description	Dicloromezotiaz is a potent insecticide acting on nicotinic acetylcholine receptors (nAChRs). Dicloromezotiaz can be used to control a broad range of lepidoptera[1].
Related Catalog	Research Areas >> Infection Signaling Pathways >> Membrane Transporter/Ion Channel >> nAChR Signaling Pathways >> Neuronal Signaling >> nAChR
In Vitro	Dicloromezotiaz is a antagonist of insect nAChR channel[1].
References	[1]. Montgomery M, et al. Structural Biology-Guided Design, Synthesis, and Biological Evaluation of Novel Insect Nicotinic Acetylcholine Receptor Orthosteric Modulators [published correction appears in J Med Chem. 2022 Mar 10;65(5):4401-4402]. J Med Chem. 2022;65(3):2297-2312.