13878-10-9

13878-10-9 structure

Name: (-)-4-(2-Chlorobenzyl)-5-oxo-4-phenylhexanoic acid
Chemical Name: 4-(2-Chlorobenzyl)-5-oxo-4-phenylhexanoic acid
CAS Number: 13878-10-9
Molecular Formula: C₁₉H₁₉ClO₃
Molecular Weight: 330.805
Catalog: Signaling Pathways Anti-infection Influenza Virus
Create Date: 2021-09-10 15:58:40
Modify Date: 2024-01-11 22:24:27
Caprochlorone has antiviral activity against orthopoxvirus. Caprochlorone can inhibit cell penetration by virus, also delays release of newly formed virus from the cell. Caprochlorone decreases the titers of influenza virus in infected-mice lungs[1][2][3].

Name	4-(2-Chlorobenzyl)-5-oxo-4-phenylhexanoic acid
Synonyms	Benzenepentanoic acid, γ-acetyl-2-chloro-γ-phenyl- 4-(2-Chlorobenzyl)-5-oxo-4-phenylhexanoic acid

Description	Caprochlorone has antiviral activity against orthopoxvirus. Caprochlorone can inhibit cell penetration by virus, also delays release of newly formed virus from the cell. Caprochlorone decreases the titers of influenza virus in infected-mice lungs[1][2][3].
Related Catalog	Signaling Pathways >> Anti-infection >> Influenza Virus Research Areas >> Infection
Target	Orthopoxvirus, Influenza[2]
References	[1]. Smee DF, Sidwell RW. A review of compounds exhibiting anti-orthopoxvirus activity in animal models. Antiviral Res. 2003;57(1-2):41-52. [2]. Stanfield FJ, Haff RF, Stewart RC. The antiviral activity of caprochlorone. Proc Soc Exp Biol Med. 1967;125(1):297-303. [3]. LIU OC, et al. Studies on the chemotherapy of viral infections. II. The effect of caprochlorone on influenza virus infections in mice. J Immunol. 1957;78(3):222-227.