57710-64-2

57710-64-2 structure

Name: 1,1'-[(2E,4E,6E,8E,10E,12E,14E)-2,6,11,15-tetramethyl-2,4,6,8,10,12,14-hexadecaheptaenedioate]-b-D-Glucopyranose
Chemical Name: Dicrocin
CAS Number: 57710-64-2
Molecular Formula: C₃₂H₄₄O₁₄
Molecular Weight: 652.683
Catalog: Research Areas Others
Create Date: 2021-09-11 19:52:06
Modify Date: 2024-01-06 20:18:28
Crocin IV (Dicrocin), a crocetin glycoside, is a carotenoid pigment. Crocin IV has potent antioxidant activity[1].

Name	Dicrocin
Synonyms	Dicrocin (2S,3R,4S,5S,6R)-3,4,5-Trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl (3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl (2E,4E,6E,8E,10E,12E,14E)-2,6,11,15-tetramethyl-2,4,6,8,10,12,14-hexadecaheptaenedioate

Description	Crocin IV (Dicrocin), a crocetin glycoside, is a carotenoid pigment. Crocin IV has potent antioxidant activity[1].
Related Catalog	Research Areas >> Others Signaling Pathways >> Others >> Others
In Vitro	Crocin IV (Dicrocin; 10 μM; 24 hours) has little or no effect on the prolongation of cell survival in PC12 cell[1]. Crocin IV enhances γ-GCS mRNA expression in serum-deprived and hypoxic PC12 cells[1]. Measurements of cell viability, peroxidized membrane lipids and caspase-3 activity showed that the rank order of the neuroprotective potency at a concentration of 10 μM is crocin>tricrocin>dicrocin and picrocrocin (the latter two crocins had a little or no potency)[1].
References	[1]. Takashi Ochiai, et al. Protective effects of carotenoids from saffron on neuronal injury in vitro and in vivo. Biochim Biophys Acta. 2007 Apr;1770(4):578-84.