Shanghai Nianxing Industrial Co., Ltd
China
Product Name: PD 174265
Price: Check
Purity: 98.0%
Stocking Period: 10 Day
Contact: Yang
Email: sales@echemcloud.com

DC Chemicals Limited
China
Product Name: PD 174265
Price: $Inquiry/100mg $Inquiry/250mg $Inquiry/1g
Purity: 98.0%
Stocking Period: 3 Day
Contact: Tony Cao
Email: sales@dcchemicals.com

Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: PD 174265
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Stocking Period: Inquiry
Contact: Ms Wang
Email: enquiry@dycnchem.com

216163-53-0

216163-53-0 structure

216163-53-0 structure

Name: PD 174265
Chemical Name: 4-N-(3-bromophenyl)-6-N-but-1-en-2-ylquinazoline-4,6-diamine
CAS Number: 216163-53-0
Molecular Formula: C₁₇H₁₅BrN₄O
Molecular Weight: 371.23100
Catalog: Signaling Pathways JAK/STAT Signaling EGFR
Create Date: 2016-08-14 13:18:12
Modify Date: 2025-08-30 12:39:19
PD 174265 is a potent, cell-permeable, reversible, and selective inhibitor of EGFR with an IC50 of 450 pM[1].

Name	4-N-(3-bromophenyl)-6-N-but-1-en-2-ylquinazoline-4,6-diamine

Description	PD 174265 is a potent, cell-permeable, reversible, and selective inhibitor of EGFR with an IC50 of 450 pM[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> JAK/STAT Signaling >> EGFR Signaling Pathways >> Protein Tyrosine Kinase/RTK >> EGFR
References	[1]. Fry DW, et al. Specific, irreversible inactivation of the epidermal growth factor receptor and erbB2, by a new class of tyrosine kinase inhibitor. Proc Natl Acad Sci U S A. 1998 Sep 29;95(20):12022-7.

Molecular Formula	C₁₇H₁₅BrN₄O
Molecular Weight	371.23100
Exact Mass	370.04300
PSA	66.91000
LogP	4.63040

79-03-8 structure

79-03-8

169205-78-1 structure

169205-78-1

~47%

216163-53-0 structure

216163-53-0

Literature: Warner-Lambert Company Patent: US6344459 B1, 2002 ; Location in patent: Page column 61-62 ; US 6344459 B1

Precursor 2
79-03-8 169205-78-1
DownStream 0

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