121028-49-7

121028-49-7 structure

Name: Secretin (rat)
Chemical Name: Secretin (rat)
CAS Number: 121028-49-7
Molecular Formula: C₁₂₉H₂₁₆N₄₂O₄₂
Molecular Weight: 3027.35000
Catalog: Peptides
Create Date: 2017-08-22 07:59:11
Modify Date: 2025-08-21 10:11:43
Secretin (33-59), rat is a 27-aa peptide, acts on secretin receptor, enhances the secretion of bicarbonate, enzymes, and K+ from the pancreas.

Name	Secretin (rat)
Synonyms	HIS-SER-ASP-GLY-THR-PHE-THR-SER-GLU-LEU-SER-ARG-LEU-GLN-ASP-SER-ALA-ARG-LEU-GLN-ARG-LEU-LEU-GLN-GLY-LEU-VAL-NH2 RAT H-His-Ser-Asp-Gly-Thr-Phe-Thr-Ser-Glu-Leu-Ser-Arg-Leu-Gln-Asp-Ser-Ala-Arg-Leu-Gln-Arg-Leu-Leu-Gln-Gly-Leu-Val-NH2 HSDGTFTSELSRLQDSARLQRLLQGLV-NH2 HIS-SER-ASP-GLY-THR-PHE-THR-SER-GLU-LEU-SER-ARG-LEU-GLN-ASP-SER-ALA-ARG-LEU-GLN-ARG-LEU-LEU-GLN-GLY-LEU-VAL-NH2 Secretin (33-59), rat

Description	Secretin (33-59), rat is a 27-aa peptide, acts on secretin receptor, enhances the secretion of bicarbonate, enzymes, and K+ from the pancreas.
Related Catalog	Signaling Pathways >> Others >> Others Research Areas >> Neurological Disease Peptides
Target	Secretin receptor[2]
In Vitro	Secretin (33-59), rat inhibits adrenocorticotropic hormone (ACTH) release, and selectively suppresses the glucocorticoid response to ACTH of dispersed zona fasciculata-reticularis (ZF/R) cells[1]. Secretin retrograde messenger to facilitate GABA transmission in the rat cerebellum[2].
References	[1]. Nussdorfer GG, et al. Secretin, glucagon, gastric inhibitory polypeptide, parathyroid hormone, and related peptides in the regulation of the hypothalamus- pituitary-adrenal axis. Peptides. 2000 Feb;21(2):309-24. [2]. Ng SS, et al. Secretin as a neuropeptide. Mol Neurobiol. 2002 Aug;26(1):97-107.