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75689-93-9

75689-93-9 structure
75689-93-9 structure
  • Name: Imanixil
  • Chemical Name: 4-amino-3-ethoxybenzenesulfonic acid
  • CAS Number: 75689-93-9
  • Molecular Formula: C17H17F3N6O2
  • Molecular Weight: 394.35100
  • Catalog: Signaling Pathways Others Others
  • Create Date: 2018-07-25 00:05:38
  • Modify Date: 2024-01-14 15:47:21
  • Imanixil (HOE-402 free base) is an inducer of the LDL receptor (LDLR). Imanixil (HOE-402 free base) is also a potent cholesterol-lowering compound, which inhibits very low density-lipoprotein (VLDL) production, and consequently attenuates atherosclerosis development[1].

Name 4-amino-3-ethoxybenzenesulfonic acid
Description Imanixil (HOE-402 free base) is an inducer of the LDL receptor (LDLR). Imanixil (HOE-402 free base) is also a potent cholesterol-lowering compound, which inhibits very low density-lipoprotein (VLDL) production, and consequently attenuates atherosclerosis development[1].
Related Catalog
References

[1]. Draijer R, et al. HOE 402 lowers serum cholesterol levels by reducing VLDL-lipid production, and not by induction of the LDL receptor, and reduces atherosclerosis in wild-type and LDL receptor-deficient mice. Biochem Pharmacol. 2002 May 1;63(9):1755-61.

Density 1.428g/cm3
Molecular Formula C17H17F3N6O2
Molecular Weight 394.35100
Exact Mass 394.13700
PSA 113.24000
LogP 3.68610
Index of Refraction 1.601

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75689-93-9 structure

75689-93-9

Literature: Kampe, Klaus-Dieter Angewandte Chemie, 1982 , vol. 94, # 7 p. 543 - 544
Precursor  2

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