1854034-70-0

1854034-70-0 structure
1854034-70-0 structure
  • Name: Bis-sulfone-PEG4-DBCO
  • Chemical Name: Bis-sulfone-PEG4-DBCO
  • CAS Number: 1854034-70-0
  • Molecular Formula: C54H59N3O12S2
  • Molecular Weight: 1006.19
  • Catalog: Signaling Pathways PROTAC PROTAC Linker
  • Create Date: 2021-09-10 16:49:07
  • Modify Date: 2024-01-07 00:36:13
  • Bis-sulfone-PEG4-DBCO is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name Bis-sulfone-PEG4-DBCO
Description Bis-sulfone-PEG4-DBCO is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. Nalawansha DA, et al. PROTACs: An Emerging Therapeutic Modality in Precision Medicine. Cell Chem Biol. 2020;27(8):998-1014.

Molecular Formula C54H59N3O12S2
Molecular Weight 1006.19
Storage condition -20°C