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2055353-77-8

2055353-77-8 structure
2055353-77-8 structure
  • Name: Mal-amido-PEG3-NHS ester
  • Chemical Name: Mal-amido-PEG3-NHS ester
  • CAS Number: 2055353-77-8
  • Molecular Formula: C20H27N3O10
  • Molecular Weight: 469.44
  • Catalog: Signaling Pathways PROTAC PROTAC Linker
  • Create Date: 2021-09-09 18:06:50
  • Modify Date: 2024-01-10 12:34:17
  • Mal-amido-PEG3-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name Mal-amido-PEG3-NHS ester
Description Mal-amido-PEG3-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. Nalawansha DA, et al. PROTACs: An Emerging Therapeutic Modality in Precision Medicine. Cell Chem Biol. 2020;27(8):998-1014.

Molecular Formula C20H27N3O10
Molecular Weight 469.44