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2512228-06-5

2512228-06-5 structure
2512228-06-5 structure
  • Name: Propargyl-PEG2-NHS ester
  • Chemical Name: Propargyl-PEG2-NHS ester
  • CAS Number: 2512228-06-5
  • Molecular Formula: C12H15NO6
  • Molecular Weight: 269.25
  • Catalog: Signaling Pathways PROTAC PROTAC Linker
  • Create Date: 2021-09-08 21:03:37
  • Modify Date: 2024-01-09 11:03:44
  • Propargyl-PEG2-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name Propargyl-PEG2-NHS ester
Description Propargyl-PEG2-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. Nalawansha DA, et al. PROTACs: An Emerging Therapeutic Modality in Precision Medicine. Cell Chem Biol. 2020;27(8):998-1014.

Molecular Formula C12H15NO6
Molecular Weight 269.25