Shanghai Nianxing Industrial Co., Ltd
China
Product Name: Antitumor agent-28
Price: Check
Purity: 98.0%
Stocking Period: 10 Day
Contact: Yang
Email: sales@echemcloud.com

2097499-67-5

2097499-67-5 structure

2097499-67-5 structure

Name: Antitumor agent-28
Chemical Name: Antitumor agent-28
CAS Number: 2097499-67-5
Molecular Formula: C₂₅H₃₂N₆O₄S
Molecular Weight: 512.62
Catalog: Signaling Pathways Cell Cycle/DNA Damage ATM/ATR
Create Date: 2021-09-05 18:33:55
Modify Date: 2025-08-27 17:16:51
Antitumor agent-28 selectively inhibits ataxia telangiectasia mutated (ATM) kinase. Antitumor agent-28 prevents ATM mediated disease and has potent anti-cancer activity[1].

Name	Antitumor agent-28

Description	Antitumor agent-28 selectively inhibits ataxia telangiectasia mutated (ATM) kinase. Antitumor agent-28 prevents ATM mediated disease and has potent anti-cancer activity[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Cell Cycle/DNA Damage >> ATM/ATR Signaling Pathways >> PI3K/Akt/mTOR >> ATM/ATR
Target	ATM ATR
In Vitro	Antitumor agent-28 inhibits ataxia telangiectasia mutated (ATM; IC50=7.6 nM; HT29 cells), ataxia telangiectasia and Rad3-related protein (ATR; IC50=18 μM; HT29 cells), PI3Ka (IC50=0.24 μM; BT474 cells). Antitumor agent-28 does not inhibit mTOR in MDA-MB-468 cells[1].
References	[1]. Kurt Gordon Pike, et al. Composés imidazo[4,5c]quinoline-2-one et leur utilisation dans le traitement du cancer. WO2017076898A1.

Molecular Formula	C₂₅H₃₂N₆O₄S
Molecular Weight	512.62

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.