2511248-11-4
2511248-11-4 structure
- Name: DHODH-IN-16
- Chemical Name: DHODH-IN-16
- CAS Number: 2511248-11-4
- Molecular Formula: C24H25FN4O3
- Molecular Weight: 436.48
- Catalog: Signaling Pathways Cell Cycle/DNA Damage DNA/RNA Synthesis
- Create Date: 2021-09-11 19:52:01
- Modify Date: 2024-01-09 01:53:27
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DHODH-IN-16 is a potent dihydroorotate dehydrogenase (DHODH) inhibitor with an IC50 of 0.396 nM for human DHODH[1].
| Name | DHODH-IN-16 |
|---|
| Description | DHODH-IN-16 is a potent dihydroorotate dehydrogenase (DHODH) inhibitor with an IC50 of 0.396 nM for human DHODH[1]. |
|---|---|
| Related Catalog | |
| Target |
IC50: 0.396 nM (human DHODH)[1] |
| In Vitro | DHODH-IN-16 (Example 22) potently inhibits the growth of MOLM-13 cells with an IC50 of 0.2 nM[1]. |
| References |
[1]. Scott Kuduk, et al. Dihydroorotate dehydrogenase inhibitors. WO2020212897A1. |
| Molecular Formula | C24H25FN4O3 |
|---|---|
| Molecular Weight | 436.48 |