222556-71-0

222556-71-0 structure

Name: Ga(III) protoporphyrin IX
Chemical Name: Ga(III) protoporphyrin IX
CAS Number: 222556-71-0
Molecular Formula: C₃₄H₃₁GaN₄O₄
Molecular Weight: 629.36
Catalog: Signaling Pathways Anti-infection Bacterial
Create Date: 2021-09-10 11:08:07
Modify Date: 2024-01-09 17:00:02
Ga(III)protoporphyrin-IX is a model for the key interporphyrin interactions in malaria pigment. Ga(III)protoporphyrin-IX acts as a potent antibacterial against gram-negative, gram-positive, and acid-fast bacteria. Ga(III)protoporphyrin-IX is readily soluble in methanol (MeOH). Ga(III)protoporphyrin IX are as malarial pigment analogues for drug development and as potential antibacterial agents[1].

Name	Ga(III) protoporphyrin IX

Description	Ga(III)protoporphyrin-IX is a model for the key interporphyrin interactions in malaria pigment. Ga(III)protoporphyrin-IX acts as a potent antibacterial against gram-negative, gram-positive, and acid-fast bacteria. Ga(III)protoporphyrin-IX is readily soluble in methanol (MeOH). Ga(III)protoporphyrin IX are as malarial pigment analogues for drug development and as potential antibacterial agents[1].
Related Catalog	Research Areas >> Infection Signaling Pathways >> Anti-infection >> Bacterial
In Vitro	Ga(III)protoporphyrin-IX has also been shown to bind to heme containing proteins and enzymes when it is included in the cellular growth medium of the Grampositive bacteria Enterococcus faecalis which does not depend on heme for cell growth. Ga(III)protoporphyrin-IX has shown to be a suitable mimic of heme and has potential applications in heme replacement/substitution[1].
References	[1]. Pinter TB, et al. Spectroscopic and theoretical studies of Ga(III)protoporphyrin-IX and its reactions with myoglobin. Inorg Chem. 2012;51(6):3743-3753.

Molecular Formula	C₃₄H₃₁GaN₄O₄
Molecular Weight	629.36