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  • DC Chemicals Limited
  • China
  • Product Name: SiR-COOH
  • Price: ¥Inquiry/100mg ¥Inquiry/250mg ¥Inquiry/1g
  • Purity: 98.0%
  • Stocking Period: 1 Day
  • Contact: Tony Cao

1418275-26-9

1418275-26-9 structure
1418275-26-9 structure
  • Name: SiR-COOH
  • Chemical Name: SiR-COOH
  • CAS Number: 1418275-26-9
  • Molecular Formula: C27H28N2O4Si
  • Molecular Weight: 472.61
  • Catalog: Research Areas Cancer
  • Create Date: 2021-11-01 09:56:47
  • Modify Date: 2024-01-03 20:31:37
  • SiR-COOH could be used to follow the intracellular location of the model therapeutic drug in GFP cells (Abs, 645 nm; Em, 676 nm)[1].

Name SiR-COOH
Description SiR-COOH could be used to follow the intracellular location of the model therapeutic drug in GFP cells (Abs, 645 nm; Em, 676 nm)[1].
Related Catalog
In Vitro SiR-COOH could be used to conjugated inhibitors such as UNC2025 (Mer inhibitor). SiR-COOH is especially useful for small-molecule probes: it exhibits bright photostable fluorescence at near-infrared wavelengths, which are ideal for imaging deep through tissue; fluorescence is robust across physiological environments with little toxicity; it is amenable to super-resolution microscopy; and it exhibits an optimal degree of hydrophilicity for live-cell imaging[2].
References

[1]. Eunha Kim, et al. Red Si-rhodamine drug conjugates enable imaging in GFP cells. Chem Commun (Camb). 2014 May 4;50(34):4504-7.

[2]. Miles A Miller, et al. Near infrared imaging of Mer tyrosine kinase (MERTK) using MERi-SiR reveals tumor associated macrophage uptake in metastatic disease. Chem Commun (Camb). 2017 Dec 19;54(1):42-45.https://pubmed.ncbi.nlm.nih.gov/29185561

Molecular Formula C27H28N2O4Si
Molecular Weight 472.61