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5250-02-2

5250-02-2 structure
5250-02-2 structure

Name 3-(Dimethylamino)-1-(4-methylphenyl)propan-1-one Hydrochloride
Synonyms 3-DiMethylaMino-1-(4-Methoxyphenyl)Propan-1-One Hydrochloride
3-(DIMETHYLAMINO)-4'-METHYLPROPIOPHENONE HYDROCHLORIDE
Boiling Point 318.2ºC at 760mmHg
Molecular Formula C12H18ClNO
Molecular Weight 227.73000
Flash Point 146.2ºC
Exact Mass 227.10800
PSA 20.31000
LogP 2.93140

CHEMICAL IDENTIFICATION

RTECS NUMBER :
UH0875000
CHEMICAL NAME :
Propiophenone, 3-(dimethylamino)-4'-methyl-, hydrochloride
CAS REGISTRY NUMBER :
5250-02-2
LAST UPDATED :
199203
DATA ITEMS CITED :
2
MOLECULAR FORMULA :
C12-H17-N-O.Cl-H
MOLECULAR WEIGHT :
227.76

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
400 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
FATOAO Farmakologiya i Toksikologiya (Moscow). For English translation, see PHTXA6 and RPTOAN. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.2- 1939- Volume(issue)/page/year: 25,437,1962
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
275 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
PCJOAU Pharmaceutical Chemistry Journal (English Translation). Translation of KHFZAN. (Plenum Pub. Corp., 233 Spring St., New York, NY 10013) No.1- 1967- Volume(issue)/page/year: 24,833,1990
HS Code 2922399090

~85%

5250-02-2 structure

5250-02-2

Literature: Hon, Wai Lam; Murray, Gordon J.; Firth, James D. Organic Letters, 2005 , vol. 7, # 25 p. 5743 - 5746

~79%

5250-02-2 structure

5250-02-2

Literature: Stauffer Chemical Company Patent: US4250185 A1, 1981 ;

~%

5250-02-2 structure

5250-02-2

Literature: Heterocyclic Communications, , vol. 11, # 2 p. 135 - 138
HS Code 2922399090
Summary 2922399090 other amino-aldehydes, amino-ketones and amino-quinones, other than those containing more than one kind of oxygen function; salts thereof VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%