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1211333-20-8

1211333-20-8 structure
1211333-20-8 structure
  • Name: [18F]AZD4694 Precursor
  • Chemical Name: 2-Methyl-2-propanyl {5-[5-(ethoxymethoxy)-1-benzofuran-2-yl]-6-nitro-2-pyridinyl}methylcarbamate
  • CAS Number: 1211333-20-8
  • Molecular Formula: C22H25N3O7
  • Molecular Weight: 443.45
  • Catalog: Research Areas Others
  • Create Date: 2021-12-24 17:53:34
  • Modify Date: 2024-01-12 21:06:27
  • [18F]AZD4694 Precursor is the precursor of [18F] AZD4694 for the synthesis of [18F] AZD4694, an amyloid-β imaging ligand with high affinity for amyloid-β plaques[1].

Name 2-Methyl-2-propanyl {5-[5-(ethoxymethoxy)-1-benzofuran-2-yl]-6-nitro-2-pyridinyl}methylcarbamate
Synonyms 2-Methyl-2-propanyl {5-[5-(ethoxymethoxy)-1-benzofuran-2-yl]-6-nitro-2-pyridinyl}methylcarbamate
Carbamic acid, N-[5-[5-(ethoxymethoxy)-2-benzofuranyl]-6-nitro-2-pyridinyl]-N-methyl-, 1,1-dimethylethyl ester
Description [18F]AZD4694 Precursor is the precursor of [18F] AZD4694 for the synthesis of [18F] AZD4694, an amyloid-β imaging ligand with high affinity for amyloid-β plaques[1].
Related Catalog
In Vitro 18F-AZD4694 is an amyloid-β imaging ligand with high affinity for amyloid-β plaques. 18F-AZD4694 is a high affinity (Kd= 2.3 nM) radioligand for imaging amyloid-β plaques that displays lower white matter binding compared to other fluorinated amyloid-PET tracers, enabling easier visual reads[1].
References

[1]. Therriault J, et al. Determining Amyloid-β Positivity Using 18F-AZD4694 PET Imaging. J Nucl Med. 2021;62(2):247-252.

Density 1.3±0.1 g/cm3
Boiling Point 593.4±50.0 °C at 760 mmHg
Molecular Formula C22H25N3O7
Molecular Weight 443.45
Flash Point 312.7±30.1 °C
Exact Mass 443.169250
LogP 3.65
Vapour Pressure 0.0±1.7 mmHg at 25°C
Index of Refraction 1.594