748120-01-6

748120-01-6 structure

Name: Nerindocianine
Chemical Name: Irdye 800Bk
CAS Number: 748120-01-6
Molecular Formula: C₄₄H₅₂N₂O₁₆S₅
Molecular Weight: 1025.21
Catalog: Research Areas Others
Create Date: 2022-03-03 09:29:17
Modify Date: 2025-08-25 21:22:18
Nerindocianine is a fluorescent diagnostic contrast agent. Nerindocianine is highly hydrophilic and is primarily metabolized by the kidneys, allowing for a non-invasive intraoperative ureteral imaging[1].

Name	Irdye 800Bk
Synonyms	3H-Indolium, 2-[(E)-2-[3-[(2E)-2-[1,3-dihydro-3,3-dimethyl-5-sulfo-1-(4-sulfobutyl)-2H-indol-2-ylidene]ethylidene]-2-(4-sulfophenoxy)-1-cyclohexen-1-yl]ethenyl]-3,3-dimethyl-5-sulfo-1-(4-sulfobutyl)-, inner salt Irdye 800Bk 4-(2-{(E)-2-[3-{(2E)-2-[3,3-Dimethyl-5-sulfo-1-(4-sulfobutyl)-1,3-dihydro-2H-indol-2-ylidene]ethylidene}-2-(4-sulfophenoxy)-1-cyclohexen-1-yl]vinyl}-3,3-dimethyl-5-sulfo-3H-indolium-1-yl)-1-butanesulfonate

Description	Nerindocianine is a fluorescent diagnostic contrast agent. Nerindocianine is highly hydrophilic and is primarily metabolized by the kidneys, allowing for a non-invasive intraoperative ureteral imaging[1].
Related Catalog	Research Areas >> Others Signaling Pathways >> Others >> Others
In Vivo	Nerindocianine (0.15 mg/kg; i.v.) shows a satisfactory visualization[1]. Animal Model: Female pigs[1] Dosage: 0.15 mg/kg Administration: I.v. Result: Showed a satisfactory visualization.
References	[1]. Barberio M, et al. Intraoperative ureter identification with a novel fluorescent catheter. Sci Rep. 2021;11(1):4501. Published 2021 Feb 24.