1709886-74-7
1709886-74-7 structure
- Name: Tominersen
- Chemical Name: Tominersen
- CAS Number: 1709886-74-7
- Molecular Formula:
- Molecular Weight:
- Catalog: Research Areas Neurological Disease
- Create Date: 2021-12-23 22:15:25
- Modify Date: 2025-08-25 12:27:16
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Tominersen (RG6042) is a second-generation 2′-O-(2-methoxyethyl) antisense oligonucleotide that targets huntingtin protein (HTT) mRNA and potently suppresses HTT production. Tominersen can be used for the research of Huntington’s disease[1].
| Name | Tominersen |
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| Description | Tominersen (RG6042) is a second-generation 2′-O-(2-methoxyethyl) antisense oligonucleotide that targets huntingtin protein (HTT) mRNA and potently suppresses HTT production. Tominersen can be used for the research of Huntington’s disease[1]. |
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| In Vitro | Tominersen binds to its cognate mRNA by means of Watson-Crick base-pair interactions, triggering RNase H1-mediated degradation of the target mRNA[1]. |
| References |
| No Any Chemical & Physical Properties |