143485-51-2

143485-51-2 structure

Name: Eltoprazine Dihydrochloride
Chemical Name: Eltoprazine Dihydrochloride
CAS Number: 143485-51-2
Molecular Formula: C₁₂H₁₈Cl₂N₂O₂
Molecular Weight: 293.19
Catalog: Signaling Pathways GPCR/G Protein 5-HT Receptor
Create Date: 2022-03-14 11:13:32
Modify Date: 2024-07-13 18:12:43
Eltoprazine (DU 28853) dihydrochloride is a 5-HT1A/5-HT1B receptors agonist and a 5-HT2C receptor antagonist. Eltoprazine dihydrochloride shows antiaggressive and anxiogenic effects[1][2].

Name	Eltoprazine Dihydrochloride

Description	Eltoprazine (DU 28853) dihydrochloride is a 5-HT1A/5-HT1B receptors agonist and a 5-HT2C receptor antagonist. Eltoprazine dihydrochloride shows antiaggressive and anxiogenic effects[1][2].
Related Catalog	Research Areas >> Neurological Disease Signaling Pathways >> GPCR/G Protein >> 5-HT Receptor Signaling Pathways >> Neuronal Signaling >> 5-HT Receptor
References	[1]. Sijbesma H, et al. Eltoprazine, a drug which reduces aggressive behaviour, binds selectively to 5-HT1 receptor sites in the rat brain: an autoradiographic study. Eur J Pharmacol. 1990 Feb 20;177(1-2):55-66. [2]. Rocha B, et al. Chronic mianserin or eltoprazine treatment in rats: effects on the elevated plus-maze test and on limbic 5-HT2C receptor levels. Eur J Pharmacol. 1994 Sep 1;262(1-2):125-31.