2649372-20-1
2649372-20-1 structure
- Name: B-Raf IN 2
- Chemical Name: B-Raf IN 2
- CAS Number: 2649372-20-1
- Molecular Formula: C20H17F2N5O4S
- Molecular Weight: 461.44
- Catalog: Signaling Pathways MAPK/ERK Pathway Raf
- Create Date: 2022-02-20 16:17:27
- Modify Date: 2026-08-15 12:19:04
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B-Raf IN 2 is a potent and selective BRAF inhibitor extracted from patent WO2021116055A1, compound Ia. B-Raf IN 2 can be used for the research of cancer[1].
| Name | B-Raf IN 2 |
|---|---|
| Synonyms |
1-Pyrrolidinesulfonamide, N-[2-cyano-3-[(3,4-dihydro-3-methyl-4-oxo-6-quinazolinyl)oxy]-4-fluorophenyl]-3-fluoro-, (3R)
BRaf IN 2,B Raf IN 2 BRAF inhibitor Compound Ia (R)-N-(2-cyano-4-fluoro-3-((3-methyl-4-oxo-3,4-dihydroquinazolin-6-yl)oxy)phenyl)-3-fluoropyrrolidine-1-sulfonamide RG6344(RO7276389) |
| Description | B-Raf IN 2 is a potent and selective BRAF inhibitor extracted from patent WO2021116055A1, compound Ia. B-Raf IN 2 can be used for the research of cancer[1]. |
|---|---|
| Related Catalog | |
| Target |
BRafV600E |
| In Vitro | B-Raf IN 2 shows considerably less paradoxial activation of the MAPK signaling pathway while retaining high potency[1]. |
| References |
[1]. Dolente C, et, al. New methylquinazolinone derivatives. WO2021116055A1. |
| Molecular Formula | C20H17F2N5O4S |
|---|---|
| Molecular Weight | 461.44 |