2138441-25-3

2138441-25-3 structure

Name: Lenalidomide-C5-amido-Boc
Chemical Name: Lenalidomide-C5-amido-Boc
CAS Number: 2138441-25-3
Molecular Formula: C₂₃H₃₁N₃O₅
Molecular Weight: 429.51
Catalog: Signaling Pathways PROTAC E3 Ligase Ligand-Linker Conjugate
Create Date: 2022-03-11 08:25:43
Modify Date: 2024-01-09 15:21:53
Lenalidomide-C5-amido-Boc is the Lenalidomide-based Cereblon ligand used in the recruitment of CRBN protein. Lenalidomide-C5-amido-Boc can be connected to the ligand for protein by a linker to form PROTAC[1].

Name	Lenalidomide-C5-amido-Boc

Description	Lenalidomide-C5-amido-Boc is the Lenalidomide-based Cereblon ligand used in the recruitment of CRBN protein. Lenalidomide-C5-amido-Boc can be connected to the ligand for protein by a linker to form PROTAC[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> E3 Ligase Ligand-Linker Conjugate
Target	Cereblon
References	[1]. Wang, Shaomeng, et al. Preparation of phthalimide-based compounds as monofunctional intermediates for ligand-dependent target protein degradation. World Intellectual Property Organization, WO2017176958 A1 2017-10-12. [2]. Robbins, Daniel, et al. WBifunctional compounds for degrading BTK via ubiquitin proteasome pathway. World Intellectual Property Organization, WO2021091575 A1 2021-05-14.

Molecular Formula	C₂₃H₃₁N₃O₅
Molecular Weight	429.51