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2428423-77-0

2428423-77-0 structure

2428423-77-0 structure

Name: Chk1-IN-6
Chemical Name: Chk1-IN-6
CAS Number: 2428423-77-0
Molecular Formula: C₁₆H₁₈F₃N₇
Molecular Weight: 365.36
Catalog: Signaling Pathways Cell Cycle/DNA Damage Checkpoint Kinase (Chk)
Create Date: 2022-03-22 20:47:13
Modify Date: 2026-07-01 11:11:59
Chk1-IN-6 is a potent, selective, and orally bioavailable CHK1 inhibitor candidate.

Name	Chk1-IN-6
Synonyms	2-Pyridinecbonitrile, 5-[[4-[(3-amino-3-methylbutyl)amino]-5-(trifluoromethyl)-2-pyrimidinyl]amino]

Description	Chk1-IN-6 is a potent, selective, and orally bioavailable CHK1 inhibitor candidate.
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Cell Cycle/DNA Damage >> Checkpoint Kinase (Chk)
Target	Chk1
References	[1]. Jin T, et al. Discovery and Development of a Potent, Selective, and Orally Bioavailable CHK1 Inhibitor Candidate: 5-((4-((3-Amino-3-methylbutyl)amino)-5-(trifluoromethyl)pyrimidin-2-yl)amino)picolinonitrile. J Med Chem. 2021 Oct 28;64(20):15069-15090.

Molecular Formula	C₁₆H₁₈F₃N₇
Molecular Weight	365.36

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