4445-03-8

4445-03-8 structure
4445-03-8 structure
  • Name: HO-PEG18-OH
  • Chemical Name: HO-PEG18-OH
  • CAS Number: 4445-03-8
  • Molecular Formula: C36H74O19
  • Molecular Weight: 810.96
  • Catalog: Signaling Pathways PROTAC PROTAC Linker
  • Create Date: 2022-04-02 13:08:19
  • Modify Date: 2024-04-07 15:29:36
  • HO-PEG18-OH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name HO-PEG18-OH
Description HO-PEG18-OH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. Nalawansha DA, et al. PROTACs: An Emerging Therapeutic Modality in Precision Medicine. Cell Chem Biol. 2020;27(8):998-985.

Molecular Formula C36H74O19
Molecular Weight 810.96