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1662687-83-3

1662687-83-3 structure

1662687-83-3 structure

Name: Mal-PEG2-Val-Cit-PABA
Chemical Name: Mal-PEG2-Val-Cit-PABA
CAS Number: 1662687-83-3
Molecular Formula: C₂₇H₃₈N₆O₉
Molecular Weight: 590.63
Catalog: Signaling Pathways Antibody-drug Conjugate ADC Linker
Create Date: 2022-03-23 12:02:26
Modify Date: 2026-09-21 13:11:57
Mal-PEG2-Val-Cit-PABA is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

Name	Mal-PEG2-Val-Cit-PABA
Synonyms	2-[2-(2,5-Dioxo-2,5-dihydro-1H-pyrrol-1-yl)ethoxy]ethyl [(S)-1-[[(S)-1-[[4-(Hydroxymethyl)phenyl]amino]-1-oxo-5-ureido-2-pentyl]amino]-3-methyl-1-oxo-2-butyl]cbamate 2-(2-(2,5-Dioxo-2,5-dihydro-1H-pyrrol-1-yl)ethoxy)ethyl ((S)-1-(((S)-1-((4-(hydroxymethyl)phenyl)amino)-1-oxo-5-ureidopentan-2-yl)amino)-3-methyl-1-oxobutan-2-yl)cbamate L-Ornithinamide, N-[[2-[2-(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)ethoxy]ethoxy]carbonyl]-L-valyl-N5-(aminocbonyl)-N-[4-(hydroxymethyl)phenyl]

Description	Mal-PEG2-Val-Cit-PABA is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Antibody-drug Conjugate >> ADC Linker
Target	Cleavable
In Vitro	ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker[1].
References	[1]. Beck A, et al. Strategies and challenges for the next generation of antibody-drug conjugates. Nat Rev Drug Discov. 2017;16(5):315-337.

Molecular Formula	C₂₇H₃₈N₆O₉
Molecular Weight	590.63

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