2243079-27-6

2243079-27-6 structure

Name: IACS-8779 disodium
Chemical Name: IACS-8779 disodium
CAS Number: 2243079-27-6
Molecular Formula: C₂₁H₂₃N₉Na₂O₁₀P₂S₂
Molecular Weight: 733.52
Catalog: Signaling Pathways Immunology/Inflammation STING
Create Date: 2022-04-07 12:29:32
Modify Date: 2024-01-10 00:12:40
IACS-8779 disodium is a highly potent stimulator of interferon genes (STING) agonist with robust systemic antitumor efficacy. IACS-8779 disodium shows robust activation of the STING pathway in vitro and a superior systemic anti-tumor response in the B16 murine model of melanoma[1].

Name	IACS-8779 disodium

Description	IACS-8779 disodium is a highly potent stimulator of interferon genes (STING) agonist with robust systemic antitumor efficacy. IACS-8779 disodium shows robust activation of the STING pathway in vitro and a superior systemic anti-tumor response in the B16 murine model of melanoma[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Immunology/Inflammation >> STING
References	[1]. Ager CR, et al. Discovery of IACS-8803 and IACS-8779, potent agonists of stimulator of interferon genes (STING) with robust systemic antitumor efficacy. Bioorg Med Chem Lett. 2019 Oct 15;29(20):126640.

Molecular Formula	C₂₁H₂₃N₉Na₂O₁₀P₂S₂
Molecular Weight	733.52