2734060-73-0
2734060-73-0 structure
- Name: KRAS G12C inhibitor 25
- Chemical Name: KRAS G12C inhibitor 25
- CAS Number: 2734060-73-0
- Molecular Formula: C32H41N7O2
- Molecular Weight: 555.71
- Catalog: Signaling Pathways GPCR/G Protein Ras
- Create Date: 2022-04-07 14:07:06
- Modify Date: 2026-08-22 04:19:44
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KRAS G12C inhibitor 25 is a KRAS G12C inhibitor. KRAS G12C inhibitor 25 inhibits SOSl-assisted GDP/GTP exchanging activity of KRAS-G12C mutant (IC50=0.48 nM). From WO2021216770A1 compound 3[1].
| Name | KRAS G12C inhibitor 25 |
|---|---|
| Synonyms | 2-Piperazineacetonitrile, 4-[(7R)-7-(3,4-dihydro-1(2H)-quinolinyl)-5,6,7,8-tetrahydro-2-[[(2S)-1-methyl-2-pyrrolidinyl]methoxy]-4-quinazolinyl]-1-(1-oxo-2-propen-1-yl)-, (2S) |
| Description | KRAS G12C inhibitor 25 is a KRAS G12C inhibitor. KRAS G12C inhibitor 25 inhibits SOSl-assisted GDP/GTP exchanging activity of KRAS-G12C mutant (IC50=0.48 nM). From WO2021216770A1 compound 3[1]. |
|---|---|
| Related Catalog | |
| Target |
KRas G12C |
| References |
[1]. Yimin Qian, et al. Substituted tetrahydroquinazoline compounds as kras inhibitors. WO2021216770A1. |
| Molecular Formula | C32H41N7O2 |
|---|---|
| Molecular Weight | 555.71 |