1902218-84-1

1902218-84-1 structure

Name	nAChR modulator-1

Description	nAChR modulator-1, a insecticide, is a insect nAChR orthosteric modulator[1].
Related Catalog	Research Areas >> Infection Signaling Pathways >> Membrane Transporter/Ion Channel >> nAChR Signaling Pathways >> Neuronal Signaling >> nAChR
In Vitro	nAChR modulator-1 (compound 3) inhibits three major pests, the larvae of the banded cucumber beetle Diabrotica balteata, the green peach aphid M. persicae, and the cotton leafworm Spodoptera littoralis,with EC90 values of 12.5 mg/L, 3.12 mg/L, and 500 mg/L[1].
References	[1]. Mark Montgomery, et al. Structural Biology-Guided Design, Synthesis, and Biological Evaluation of Novel Insect Nicotinic Acetylcholine Receptor Orthosteric Modulators. J Med Chem. 2022 Feb 10;65(3):2297-2312.

Molecular Formula	C₁₂H₈ClN₃O₂
Molecular Weight	261.66