1639929-29-5
1639929-29-5 structure
- Name: Chromenone 1
- Chemical Name: Chromenone 1
- CAS Number: 1639929-29-5
- Molecular Formula: C18H10F3N3O2
- Molecular Weight: 357.29
- Create Date: 2022-06-18 18:17:07
- Modify Date: 2025-08-25 12:03:59
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Chromenone 1 is a potent osteogenic bone morphogenetic protein (BMP) potentiator. Chromenone 1 exhibits a unique mode of action as it induces a pronounced, kinase-independent, negative TGFβ feedback that enhances nuclear BMP-Smad signaling outputs[1].
| Name | Chromenone 1 |
|---|
| Description | Chromenone 1 is a potent osteogenic bone morphogenetic protein (BMP) potentiator. Chromenone 1 exhibits a unique mode of action as it induces a pronounced, kinase-independent, negative TGFβ feedback that enhances nuclear BMP-Smad signaling outputs[1]. |
|---|---|
| Related Catalog | |
| In Vitro | Chromenone 1 rescues DMH-1-induced cardiogenesis (IC50=0.2 μM) and efficiently stimulates BMP-dependent osteogenesis from C2C12 myoblasts[1]. |
| References |
| Molecular Formula | C18H10F3N3O2 |
|---|---|
| Molecular Weight | 357.29 |