2607871-93-0

2607871-93-0 structure

Name: Remdesivir de(ethylbutyl 2-aminopropanoate)
Chemical Name: Remdesivir de(ethylbutyl 2-aminopropanoate)
CAS Number: 2607871-93-0
Molecular Formula: C₁₈H₁₈N₅O₇P
Molecular Weight: 447.34
Create Date: 2022-06-16 10:14:15
Modify Date: 2024-01-12 16:56:20
Remdesivir de(ethylbutyl 2-aminopropanoate) is an impurity of Remdesivir. Remdesivir, a nucleoside analogue with effective antiviral activity, has EC50s of 74 nM for SARS-CoV and MERS-CoV in HAE cells, and 30 nM for murine hepatitis virus in delayed brain tumor cells. Remdesivir is highly effective in the control of SARS-CoV-2 (COVID-19) infection in vitro[1][2].

Name	Remdesivir de(ethylbutyl 2-aminopropanoate)

Description	Remdesivir de(ethylbutyl 2-aminopropanoate) is an impurity of Remdesivir. Remdesivir, a nucleoside analogue with effective antiviral activity, has EC50s of 74 nM for SARS-CoV and MERS-CoV in HAE cells, and 30 nM for murine hepatitis virus in delayed brain tumor cells. Remdesivir is highly effective in the control of SARS-CoV-2 (COVID-19) infection in vitro[1][2].
Related Catalog	Research Areas >> Infection Signaling Pathways >> Others >> Others
References	[1]. Agostini ML, et al. Coronavirus Susceptibility to the Antiviral Remdesivir (GS-5734) Is Mediated by the Viral Polymerase and the Proofreading Exoribonuclease. MBio. 2018 Mar 6;9(2):e00221-18. [2]. Wang M, et al. Remdesivir and chloroquine effectively inhibit the recently emerged novel coronavirus (2019-nCoV) in vitro. Cell Res. 2020 Mar;30(3):269-271.

Molecular Formula	C₁₈H₁₈N₅O₇P
Molecular Weight	447.34