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2642224-24-4

2642224-24-4 structure

2642224-24-4 structure

Name: Axl-IN-5
Chemical Name: Axl-IN-5
CAS Number: 2642224-24-4
Molecular Formula: C₃₁H₃₅N₅O₂S
Molecular Weight: 541.71
Catalog: Signaling Pathways Protein Tyrosine Kinase/RTK TAM Receptor
Create Date: 2022-05-30 18:45:05
Modify Date: 2026-08-05 22:44:03
Axl-IN-5 (compound 1) is a AXL inhibitor with an IC50 of 283 nM. Axl-IN-5 has anticancer effects[1].

Name	Axl-IN-5
Synonyms	Benzenesulfonamide, N,N-dimethyl-2-[2-[[(7S)-6,7,8,9-tetrahydro-7-(1-pyrrolidinyl)-5H-benzocyclohten-2-yl]amino]-8-quinazolinyl]

Description	Axl-IN-5 (compound 1) is a AXL inhibitor with an IC50 of 283 nM. Axl-IN-5 has anticancer effects[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Protein Tyrosine Kinase/RTK >> TAM Receptor
Target	IC50: 283 nM (AXL)[1]
References	[1]. Lin-Lin Zhang, et al. Discovery a series of quinazolin derivatives as potent AXL inhibitors. Eur J Med Chem. 2022 Apr 6;237:114316.

Molecular Formula	C₃₁H₃₅N₅O₂S
Molecular Weight	541.71

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