2654075-94-0

2654075-94-0 structure

2654075-94-0 structure

Name: CDK7/12-IN-1
Chemical Name: CDK7/12-IN-1
CAS Number: 2654075-94-0
Molecular Formula: C₂₅H₃₄N₈O
Molecular Weight: 462.59
Catalog: Signaling Pathways Cell Cycle/DNA Damage CDK
Create Date: 2022-05-21 08:46:07
Modify Date: 2024-03-10 18:30:48
CDK7/12-IN-1 is a selective CDK7/12 inhibitor with IC50s of 3 and 277 nM for CDK7 and CDK 12, respectively. CDK7 and CDK12 inhibition is an effective strategy to inhibit tumour growth[1].

Name	CDK7/12-IN-1

Description	CDK7/12-IN-1 is a selective CDK7/12 inhibitor with IC50s of 3 and 277 nM for CDK7 and CDK 12, respectively. CDK7 and CDK12 inhibition is an effective strategy to inhibit tumour growth[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Cell Cycle/DNA Damage >> CDK
References	[1]. Edward AINSCOW, et al. 4-[[(7-aminopyrazolo[1,5-a]pyrimidin-5-yl)amino]methyl]piperidin-3-ol compounds and their therapeutic use. WO2021122745A1.

Molecular Formula	C₂₅H₃₄N₈O
Molecular Weight	462.59