2649837-82-9

2649837-82-9 structure

Name: HIV-1 inhibitor-19
Chemical Name: HIV-1 inhibitor-19
CAS Number: 2649837-82-9
Molecular Formula: C₂₄H₂₂BClN₂O₅S
Molecular Weight: 496.77
Catalog: Signaling Pathways Anti-infection HIV
Create Date: 2022-06-30 19:01:07
Modify Date: 2024-01-09 10:55:26
HIV-1 inhibitor-19 is a potent HIV-1 non-nucleoside reverse transcriptase inhibitor (NNRTI). HIV-1 inhibitor-19 maintains its inhibitory activity against L100I, K103N and V106A/ F227L mutant strains with EC50s of 7.3 nM, 9.2 nM and 21.0 nM, respectively[1].

Name	HIV-1 inhibitor-19

Description	HIV-1 inhibitor-19 is a potent HIV-1 non-nucleoside reverse transcriptase inhibitor (NNRTI). HIV-1 inhibitor-19 maintains its inhibitory activity against L100I, K103N and V106A/ F227L mutant strains with EC50s of 7.3 nM, 9.2 nM and 21.0 nM, respectively[1].
Related Catalog	Signaling Pathways >> Anti-infection >> HIV Research Areas >> Infection
References	[1]. Shujing Xu, et al. Indolylarylsulfones bearing phenylboronic acid and phenylboronate ester functionalities as potent HIV‑1 non-nucleoside reverse transcriptase inhibitors. Bioorg Med Chem. 2022 Jan 1;53:116531.

Molecular Formula	C₂₄H₂₂BClN₂O₅S
Molecular Weight	496.77