2244622-44-2

2244622-44-2 structure

Name: MptpB-IN-1
Chemical Name: MptpB-IN-1
CAS Number: 2244622-44-2
Molecular Formula: C₁₇H₁₁Cl₂NO₄
Molecular Weight: 364.18
Catalog: Research Areas Infection
Create Date: 2022-05-30 19:48:02
Modify Date: 2025-08-25 19:55:05
MptpB-IN-1 (Compound 13) is a potent and orally active inhibitor of MptpB. Mycobacterium tuberculosis protein-tyrosine-phosphatase B (MptpB) is a secreted virulence factor that subverts antimicrobial activity in the host. MptpB-IN-1 reduces multidrug-resistant mycobacterium tuberculosis survival and infection burden[1].

Name	MptpB-IN-1

Description	MptpB-IN-1 (Compound 13) is a potent and orally active inhibitor of MptpB. Mycobacterium tuberculosis protein-tyrosine-phosphatase B (MptpB) is a secreted virulence factor that subverts antimicrobial activity in the host. MptpB-IN-1 reduces multidrug-resistant mycobacterium tuberculosis survival and infection burden[1].
Related Catalog	Research Areas >> Infection
References	[1]. Vickers CF, et al. Structure-Based Design of MptpB Inhibitors That Reduce Multidrug-Resistant Mycobacterium tuberculosis Survival and Infection Burden in Vivo. J Med Chem. 2018;61(18):8337-8352.

Molecular Formula	C₁₇H₁₁Cl₂NO₄
Molecular Weight	364.18