2452118-54-4

2452118-54-4 structure

Name: VIM-2-IN-1
Chemical Name: VIM-2-IN-1
CAS Number: 2452118-54-4
Molecular Formula: C₁₂H₁₃IN₄O₄S
Molecular Weight: 436.23
Catalog: Signaling Pathways Anti-infection Bacterial
Create Date: 2022-05-21 21:03:19
Modify Date: 2024-01-06 04:36:42
VIM-2-IN-1 (compound 1dj) is a β-lactamase inhibitor with antibacterial activities. VIM-2-IN-1 has moderate IC50 values of 23 µM, 48 µM and 231 µM for Verona integron-encoded metallo-β-lactamase (VIM-2), German imipenemase-1 (GIM-1) and New Delhi metallo-β-lactamase (NDM-1), respectively[1].

Name	VIM-2-IN-1

Description	VIM-2-IN-1 (compound 1dj) is a β-lactamase inhibitor with antibacterial activities. VIM-2-IN-1 has moderate IC50 values of 23 µM, 48 µM and 231 µM for Verona integron-encoded metallo-β-lactamase (VIM-2), German imipenemase-1 (GIM-1) and New Delhi metallo-β-lactamase (NDM-1), respectively[1].
Related Catalog	Research Areas >> Infection Signaling Pathways >> Anti-infection >> Bacterial
Target	IC50: 23 µM (VIM-2), 48 µM (GIM-1) and 231 µM (NDM-1)[1].
References	[1]. Zeeshan Muhammad, et al. Structural studies of triazole inhibitors with promising inhibitor effects against antibiotic resistance metallo-β-lactamases. Bioorg Med Chem. 2020 Aug 1;28(15):115598.

Molecular Formula	C₁₂H₁₃IN₄O₄S
Molecular Weight	436.23