2748492-38-6

2748492-38-6 structure

2748492-38-6 structure

Name: Cyclobenzaprine-d6 hydrochloride
Chemical Name: Cyclobenzaprine-d6 hydrochloride
CAS Number: 2748492-38-6
Molecular Formula: C₂₀H₁₆D₆ClN
Molecular Weight: 317.89
Catalog: Signaling Pathways GPCR/G Protein 5-HT Receptor
Create Date: 2022-08-02 10:18:02
Modify Date: 2024-01-10 09:27:03
Cyclobenzaprine-d6 (hydrochloride) is deuterium labeled Cyclobenzaprine (hydrochloride).

Name	Cyclobenzaprine-d6 hydrochloride

Description	Cyclobenzaprine-d6 (hydrochloride) is deuterium labeled Cyclobenzaprine (hydrochloride).
Related Catalog	Research Areas >> Neurological Disease Signaling Pathways >> GPCR/G Protein >> 5-HT Receptor Signaling Pathways >> Neuronal Signaling >> 5-HT Receptor
In Vitro	Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
References	[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [2]. Kobayashi, H., Y. Hasegawa, and H. Ono, Cyclobenzaprine, a centrally acting muscle relaxant, acts on descending serotonergic systems. Eur J Pharmacol, 1996. 311(1): p. 29-35. [3]. Honda, M., T. Nishida, and H. Ono, Tricyclic analogs cyclobenzaprine, amitriptyline and cyproheptadine inhibit the spinal reflex transmission through 5-HT(2) receptors. Eur J Pharmacol, 2003. 458(1-2): p. 91-9.

Molecular Formula	C₂₀H₁₆D₆ClN
Molecular Weight	317.89