2757672-69-6

2757672-69-6 structure

Name: (S)-GFB-12811
Chemical Name: GFB-12811
CAS Number: 2757672-69-6
Molecular Formula: C₂₂H₂₃F₄N₅O
Molecular Weight: 449.4
Catalog: Signaling Pathways Cell Cycle/DNA Damage CDK
Create Date: 2022-06-30 19:15:39
Modify Date: 2026-07-29 10:44:37
(S)-GFB-12811 (compound 596) is a potent and selective CDK5 inhibitor, with an IC50 value less than 10 nM. (S)-GFB-12811 can be used in the research of cell cycle progression, neuronal development, tumorigenesis[1].

Name	GFB-12811

Description	(S)-GFB-12811 (compound 596) is a potent and selective CDK5 inhibitor, with an IC50 value less than 10 nM. (S)-GFB-12811 can be used in the research of cell cycle progression, neuronal development, tumorigenesis[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Cell Cycle/DNA Damage >> CDK Research Areas >> Neurological Disease
Target	CDK5:<10 nM (IC50) CDK2:100 nM~1 μ nM (IC50)
References	[1]. Malojcic Goran, et al. Substituted 1,6-naphthyridines as inhibitors of CDK5 and their preparation. Patent WO2022011274.