2757672-69-6

2757672-69-6 structure
2757672-69-6 structure
  • Name: (S)-GFB-12811
  • Chemical Name: GFB-12811
  • CAS Number: 2757672-69-6
  • Molecular Formula:
  • Molecular Weight:
  • Catalog: Signaling Pathways Cell Cycle/DNA Damage CDK
  • Create Date: 2022-06-30 19:15:39
  • Modify Date: 2024-04-02 11:23:36
  • (S)-GFB-12811 (compound 596) is a potent and selective CDK5 inhibitor, with an IC50 value less than 10 nM. (S)-GFB-12811 can be used in the research of cell cycle progression, neuronal development, tumorigenesis[1].

Name GFB-12811
Description (S)-GFB-12811 (compound 596) is a potent and selective CDK5 inhibitor, with an IC50 value less than 10 nM. (S)-GFB-12811 can be used in the research of cell cycle progression, neuronal development, tumorigenesis[1].
Related Catalog
Target

CDK5:<10 nM (IC50)

CDK2:100 nM~1 μ nM (IC50)

References

[1]. Malojcic Goran, et al. Substituted 1,6-naphthyridines as inhibitors of CDK5 and their preparation. Patent WO2022011274.

No Any Chemical & Physical Properties
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