2459657-11-3

2459657-11-3 structure

Name: Antibacterial agent 106
Chemical Name: Antibacterial agent 106
CAS Number: 2459657-11-3
Molecular Formula: C₂₀H₂₄N₆S
Molecular Weight: 380.51
Catalog: Signaling Pathways Anti-infection Bacterial
Create Date: 2022-07-02 13:27:13
Modify Date: 2025-08-26 09:48:32
Antibacterial agent 106 (compound 8) is an orally active and potent antibacterial agent with antibiofilm activity. Antibacterial agent 106 shows potent antibacterial effect against multi-drug resistant (MDR)-Gram positive pathogens. Antibacterial agent 106 is highly effective in clearing 99.7% of the intracellular methicillin-resistant S. aureus (MRSA) harbored inside macrophages[1].

Name	Antibacterial agent 106

Description	Antibacterial agent 106 (compound 8) is an orally active and potent antibacterial agent with antibiofilm activity. Antibacterial agent 106 shows potent antibacterial effect against multi-drug resistant (MDR)-Gram positive pathogens. Antibacterial agent 106 is highly effective in clearing 99.7% of the intracellular methicillin-resistant S. aureus (MRSA) harbored inside macrophages[1].
Related Catalog	Research Areas >> Infection Signaling Pathways >> Anti-infection >> Bacterial
In Vivo	Antibacterial agent 106 (compound 8) can penetrate gut cells and reach plasma within 15 min and maintain effective plasma concentration for around 12 h[1].
References	[1]. Hosny Y, et al. Modifying the lipophilic part of phenylthiazole antibiotics to control their drug-likeness. Eur J Med Chem. 2020 Jan 1;185:111830.

Molecular Formula	C₂₀H₂₄N₆S
Molecular Weight	380.51