2452306-13-5

2452306-13-5 structure

Name: Antibacterial agent 99
Chemical Name: Antibacterial agent 99
CAS Number: 2452306-13-5
Molecular Formula: C₂₇H₂₇BrN₂
Molecular Weight: 459.42
Catalog: Signaling Pathways Anti-infection Bacterial
Create Date: 2022-07-01 19:31:55
Modify Date: 2024-01-31 11:08:42
Antibacterial agent 99 (compound 7b) is a potent antibacterial agent. Antibacterial agent 99 shows significant antibacterial and antifungal activity. Antibacterial agent 99 dose not show haemolytic activity[1].

Name	Antibacterial agent 99

Description	Antibacterial agent 99 (compound 7b) is a potent antibacterial agent. Antibacterial agent 99 shows significant antibacterial and antifungal activity. Antibacterial agent 99 dose not show haemolytic activity[1].
Related Catalog	Research Areas >> Infection Signaling Pathways >> Anti-infection >> Bacterial
In Vitro	Antibacterial agent 99 (compound 7b) shows antimicrobial activity with MIC of 8, 8, 16 μg/mL for Sa - Staphylococcus aureus (MRSA) ATCC 43300, Ca - Candida albicansATCC 90028, Cn - Cryptococcus neoformans H99 ATCC 208821, respectively[1]. Antibacterial agent 99 shows cytotoxicity with an CC50 of 2.1 μg/mL for HEK293 cells, and haemolytic activity with an HC10 of >32 μg/mL for human red blood cells[1].
References	[1]. Demchenko S, et al. Synthesis, antibacterial and antifungal activity of new 3-biphenyl-3H-Imidazo[1,2-a]azepin-1-ium bromides. Eur J Med Chem. 2020 Sep 1;201:112477.

Molecular Formula	C₂₇H₂₇BrN₂
Molecular Weight	459.42