2077083-94-2

2077083-94-2 structure

Name: Antifungal agent 31
Chemical Name: Antifungal agent 31
CAS Number: 2077083-94-2
Molecular Formula: C₂₅H₂₂F₂N₆O₃
Molecular Weight: 492.48
Catalog: Signaling Pathways Anti-infection Fungal
Create Date: 2022-07-02 20:54:53
Modify Date: 2024-01-11 11:02:58
Antifungal agent 31 (compound 12) is a potent and orally active triazole antifungal agents with a pyrrolotriazinone scaffold. Antifungal agent 31 shows antifungal activity against Candida spp. and filamentous fungi. Antifungal agent 31 significantly reduced mortality rates and kidney fungal burden in two murine models of lethal systemic infections[1].

Name	Antifungal agent 31

Description	Antifungal agent 31 (compound 12) is a potent and orally active triazole antifungal agents with a pyrrolotriazinone scaffold. Antifungal agent 31 shows antifungal activity against Candida spp. and filamentous fungi. Antifungal agent 31 significantly reduced mortality rates and kidney fungal burden in two murine models of lethal systemic infections[1].
Related Catalog	Research Areas >> Infection Signaling Pathways >> Anti-infection >> Fungal
References	[1]. Montoir D, et al. New azole antifungals with a fused triazinone scaffold. Eur J Med Chem. 2020 Mar 1;189:112082.

Molecular Formula	C₂₅H₂₂F₂N₆O₃
Molecular Weight	492.48