2456427-48-6

2456427-48-6 structure

Name: Antitrypanosomal agent 4
Chemical Name: Antitrypanosomal agent 4
CAS Number: 2456427-48-6
Molecular Formula: C₁₈H₁₄ClN₃O₅S
Molecular Weight: 419.84
Catalog: Research Areas Infection
Create Date: 2022-07-17 20:36:46
Modify Date: 2024-01-22 16:12:06
Antitrypanosomal agent 4 (compound 19) is a potent and blood-brain barrier permeable antitrypanosomal agent. Antitrypanosomal agent 4 has good activity against Trypanosoma cruzi (T. cruzi) and Trypanosoma brucei brucei (T. b. brucei) with IC50s of 1.2 μM and 70 nM, respectively[1].

Name	Antitrypanosomal agent 4

Description	Antitrypanosomal agent 4 (compound 19) is a potent and blood-brain barrier permeable antitrypanosomal agent. Antitrypanosomal agent 4 has good activity against Trypanosoma cruzi (T. cruzi) and Trypanosoma brucei brucei (T. b. brucei) with IC50s of 1.2 μM and 70 nM, respectively[1].
Related Catalog	Research Areas >> Infection
Target	IC50: 1.2 μM (T. cruzi), 70 nM (T. b. brucei)[1]
References	[1]. Fersing C, Boudot C, Castera-Ducros C, et al. 8-Alkynyl-3-nitroimidazopyridines display potent antitrypanosomal activity against both T. b. brucei and cruzi. Eur J Med Chem. 2020;202:112558.

Molecular Formula	C₁₈H₁₄ClN₃O₅S
Molecular Weight	419.84