2766407-55-8

2766407-55-8 structure

Name: ATR-IN-18
Chemical Name: ATR-IN-18
CAS Number: 2766407-55-8
Molecular Formula: C₁₉H₂₂F₃N₇O₅S
Molecular Weight: 517.48
Catalog: Signaling Pathways Cell Cycle/DNA Damage ATM/ATR
Create Date: 2022-06-26 07:55:38
Modify Date: 2024-01-16 08:46:45
ATR-IN-18 (compound 2) is an orally active and potent ATR kinase inhibitor, with an IC50 of 0.69 nM. ATR-IN-18 shows antiproliferative activity in LoVo cells, with an IC50 of 37.34 nM. ATR-IN-18 has anti-tumor activity[1].

Name	ATR-IN-18

Description	ATR-IN-18 (compound 2) is an orally active and potent ATR kinase inhibitor, with an IC50 of 0.69 nM. ATR-IN-18 shows antiproliferative activity in LoVo cells, with an IC50 of 37.34 nM. ATR-IN-18 has anti-tumor activity[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Cell Cycle/DNA Damage >> ATM/ATR Signaling Pathways >> PI3K/Akt/mTOR >> ATM/ATR
Target	ATR:0.69 nM (IC50)
References	[1]. Xiaohui Liu, et al. Triheterocyclic derivative, and pharmaceutical composition and application thereof. WO2022078480A1.

Molecular Formula	C₁₉H₂₂F₃N₇O₅S
Molecular Weight	517.48