2634714-79-5

2634714-79-5 structure
2634714-79-5 structure
  • Name: CB2R probe 1
  • Chemical Name: CB2R probe 1
  • CAS Number: 2634714-79-5
  • Molecular Formula: C36H42N4O4
  • Molecular Weight: 594.74
  • Catalog: Signaling Pathways GPCR/G Protein Cannabinoid Receptor
  • Create Date: 2022-09-10 10:58:00
  • Modify Date: 2025-08-26 15:31:25
  • CB2R probe 1 is a safe and green CB2R (cannabinoid 2 receptor) fluorescent probe with an Ki of 130 nM. CB2R probe 1 shows low cytotoxicity in cancer cells[1].

Name CB2R probe 1
Description CB2R probe 1 is a safe and green CB2R (cannabinoid 2 receptor) fluorescent probe with an Ki of 130 nM. CB2R probe 1 shows low cytotoxicity in cancer cells[1].
Related Catalog
Target

cannabinoid type-2 receptors:130 nM (Ki)

In Vitro CB2R probe 1 (compound 28) (100 nM; 24 h) shows low cytotoxicity with IC50s of 1.6, 1.4, 1.4, 1.1, 2.6, 0.55, 2.0, 2.4, 2.8 nM for PANC1, U2OS, HT29, HT29-DX, U87AD, PC3, CB2R-HEK293, MCF7, MCFT-DX cells, respectively[1].
References

[1]. Spinelli F, et al. Design and synthesis of fluorescent ligands for the detection of cannabinoid type 2 receptor (CB2R). Eur J Med Chem. 2020 Feb 15;188:112037.

Molecular Formula C36H42N4O4
Molecular Weight 594.74
The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.