1038061-96-9

1038061-96-9 structure

Name: COX-2-IN-18
Chemical Name: COX-2-IN-18
CAS Number: 1038061-96-9
Molecular Formula: C₁₈H₁₉N₃O₃S₂
Molecular Weight: 389.49
Catalog: Signaling Pathways Immunology/Inflammation COX
Create Date: 2022-07-19 16:55:19
Modify Date: 2025-08-26 06:37:57
COX-2-IN-18 (Compound 3) is a potent inhibitor of COX-2. COX-2-IN-18 possesses good COX-2 inhibitory activity (IC50 = 0.775 μM) compared to the reference drug, Celecoxib (IC50 = 0.153 μM). COX-2-IN-18 has the potential for the research of cancer diseases[1].

Name	COX-2-IN-18

Description	COX-2-IN-18 (Compound 3) is a potent inhibitor of COX-2. COX-2-IN-18 possesses good COX-2 inhibitory activity (IC50 = 0.775 μM) compared to the reference drug, Celecoxib (IC50 = 0.153 μM). COX-2-IN-18 has the potential for the research of cancer diseases[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Immunology/Inflammation >> COX
References	[1]. El-Azab AS, et al. Antitumor activity, multitarget mechanisms, and molecular docking studies of quinazoline derivatives based on a benzenesulfonamide scaffold: Cell cycle analysis. Bioorg Chem. 2020;104:104345.

Molecular Formula	C₁₈H₁₉N₃O₃S₂
Molecular Weight	389.49