Shanghai Nianxing Industrial Co., Ltd
China
Product Name: Palmitic acid
Price: Check
Purity: 98.0%
Stocking Period: 10 Day
Contact: Yang
Email: sales@echemcloud.com

331942-46-2

331942-46-2 structure

331942-46-2 structure

Name: DHFR-IN-2
Chemical Name: DHFR-IN-2
CAS Number: 331942-46-2
Molecular Formula: C₁₄H₁₃NO₂
Molecular Weight: 227.26
Catalog: Signaling Pathways Cell Cycle/DNA Damage Antifolate
Create Date: 2022-07-02 18:02:16
Modify Date: 2024-01-15 17:05:41
DHFR-IN-2 (compound 4e) is a potent and uncompetitive inhibitor for MtDHFR (dihydrofolate reductase from M. tuberculosis), with an IC50 of 7 μM. DHFR-IN-2 can be used for tuberculosis (TB) research[1].

Name	DHFR-IN-2

Description	DHFR-IN-2 (compound 4e) is a potent and uncompetitive inhibitor for MtDHFR (dihydrofolate reductase from M. tuberculosis), with an IC50 of 7 μM. DHFR-IN-2 can be used for tuberculosis (TB) research[1].
Related Catalog	Research Areas >> Infection Signaling Pathways >> Cell Cycle/DNA Damage >> Antifolate
Target	IC50: 7 ± 0.13 μM (MtDHFR)[1]
References	[1]. Kronenberger T,et al. Design, synthesis and biological activity of novel substituted 3-benzoic acid derivatives as MtDHFR inhibitors. Bioorg Med Chem. 2020 Aug 1;28(15):115600.

Molecular Formula	C₁₄H₁₃NO₂
Molecular Weight	227.26

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.